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This Concept Map, created with IHMC CmapTools, has information related to: cell injury, cell injury due to dystrophic calcification, altered metabolic pathways from depleted ATP & active transport, cell injury due to causes, essential metabolite deficiency including oxygen deprivation, endogenous like lipid (alcohol), failure of membrane integrity due to altered membrane lipids, reversible structural chnages cytoskeleton disruption, endogenous like protein (alcohol, Alzheimer's enzyme deficiency, mechanisms of injury may include free radical generation, causes include ischemia/hypoxia, failure of membrane integrity due to lysosomal release, mechanisms of injury may include trauma, response to injury depends upon type of injury, cell injury due to intracellular accumulations, mechanisms of injury may include failure of membrane integrity, dystrophic calcification include tumor necrosis, failure of membrane integrity due to altered calcium homeostasis, reversible structural chnages membrane blebs, reversible structural chnages mitochondrial swelling, injury may be reversible