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This Concept Map, created with IHMC CmapTools, has information related to: 06. Urinary Tract Infections, Uncomplicated -Women -Normal urinary tract -Resolves quickly w/ antibiotics -No long term impact "other symptoms" Decreased urinary output is most serious since it could be a sign of underlying serious problem, Uncomplicated -Women -Normal urinary tract -Resolves quickly w/ antibiotics -No long term impact "other symptoms" -Incr. freq -Bloody/cloudy urine (due to proteins), Asymptomatic bacteriuria treatment ????, Decreased urinary output is most serious since it could be a sign of underlying serious problem associated with Complicated -Abnormal urinary tract -Antibiotic resistance -Longer therapy/ surgery -Long term impact, Other factors -Hemolysin (cytotoxic) -Aerobactin (iron) may be located on Pathogenicity islands, Cystitis treatment -Bactrim -Trimethoprim -Fluoroquinolone, URINARY TRACT INFECTIONS Ref: Pages 1005-1022 epidemiology Risk factors Host: -Prior UTI (high recurrence rate) -Family history -Second week of menstrual cycle -Vesicoureteral reflux Environmental: -Sexual activity -Spermacide / diaphragm -No relation to hygene, Uncomplicated -Women -Normal urinary tract -Resolves quickly w/ antibiotics -No long term impact can be Pyelonephritis, URINARY TRACT INFECTIONS Ref: Pages 1005-1022 epidemiology Elderly -Most common cause of bacteremia, Complicated -Abnormal urinary tract -Antibiotic resistance -Longer therapy/ surgery -Long term impact "other symptoms" -Incr. freq -Bloody/cloudy urine (due to proteins), Urine is sterile -Only one bug = culprit -Multiple bugs = contamination typical contaminants -Lactobacilli -Alpha hemolytic strep -Anaerobes, Elderly -Most common cause of bacteremia may have Asymptomatic bacteriuria, URINARY TRACT INFECTIONS Ref: Pages 1005-1022 diagnosis Definite, Urine is sterile -Only one bug = culprit -Multiple bugs = contamination Clean catch method to avoid contams -Also, don't use cath bag for urine since very contam., Complicated -Abnormal urinary tract -Antibiotic resistance -Longer therapy/ surgery -Long term impact treatment Correct underlying problems, Enterococcus -Ampicillin (or vanco) otherwise -Bactrim -Floroquinolone, Asymptomatic bacteriuria Should search for alternative sources of ifection, Pyelonephritis symptoms Fever, URINARY TRACT INFECTIONS Ref: Pages 1005-1022 either Uncomplicated -Women -Normal urinary tract -Resolves quickly w/ antibiotics -No long term impact, URINARY TRACT INFECTIONS Ref: Pages 1005-1022 bug Gram negative bacteria Enterobacteriaceae: -Kleb -Enterobacteria -Proteus Pseudomonas