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This Concept Map, created with IHMC CmapTools, has information related to: ppifailure, mechnisms of PPI failure might include Residual acid reflux, mechnisms of PPI failure might include differences in metabolism, mechnisms of PPI failure might include Other diseases, mechnisms of PPI failure might include Psychological comorbidity, mechnisms of PPI failure might include Compliance, mechnisms of PPI failure might include Drug resistance, mechnisms of PPI failure might include Delayed healing, mechnisms of PPI failure might include reduced bioavailability, mechnisms of PPI failure might include Esophageal hypersensitivity and functional heartburn, mechnisms of PPI failure might include Bile acid reflux, mechnisms of PPI failure might include Weakly acidic or alkaline reflux, mechnisms of PPI failure might include Helicobacter pylori status, mechnisms of PPI failure might include nocturnal acid breakthrough, mechnisms of PPI failure might include Proper dosing