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This Concept Map, created with IHMC CmapTools, has information related to: Heather_Hypothalamus-Pituitary_Hormones-1.cmap, Anterior Pituitary Gland TSH, Posterior Pituitary Gland Antidiuretic hormone (ADH), Anterior Pituitary Gland Growth Hormone (GH), Hyposecretion: cretinism, myxedema Hypersecretion: Grave's disease, exophthalmos Cretinism - children with severe hypothyroidism short, disproportionate body, thick tongue and neck, mental deficiencies, Antidiuretic hormone (ADH) Stimulated: increased osmolarity of blood, decreased blood volume, low BP, pain Inhibited: by adequate hydration, alcohol, Hypothalamus supraopticohypophysial nerve tract Posterior Pituitary Gland, Oxytocin (OT) Stimulated: cervical/uterine stretching, infant sucking at breast Inhibited: lack of appropriate neural stimuli, Target: thyroid gland, stimulates thyroid to release thyroid hormone Hyposecretion: cretinism, myxedema Hypersecretion: Grave's disease, exophthalmos, Anterior Pituitary Gland Prolactin, Hyposecretion: pituitary dwarfism Hypersecretion: gigantism, acromegaly Gigantism - in children, enhanced growth before epiphyseal plates close, Growth Hormone (GH) Stimulated:by GHRH release Inhibited: negative feedback by GH, Target: Liver, muscle, bone, cartilage Stimulates somatic growth, mobilizes fats Hyposecretion: pituitary dwarfism Hypersecretion: gigantism, acromegaly, Hyposecretion: cretinism, myxedema Hypersecretion: Grave's disease, exophthalmos Grave's - hyperthyroid elevated metabolic rate, sweating, rapid, irregular HR, nervousness, weight loss, Hyposecretion: diabetes insipidus Hypersecretion: SIADH SIADH - hypotonic hyponatremia thirst, impaired taste, anorexia, dyspnea, fatigue, Hyposecretion: cretinism, myxedema Hypersecretion: Grave's disease, exophthalmos Myxedema - hypothyroid in adults, due to lack of iodine low metabolic rate, chills, constipation, thick, dry skin, puffy eyes, edema, lethargy, mental sluggishness, Stimulated: increased osmolarity of blood, decreased blood volume, low BP, pain Inhibited: by adequate hydration, alcohol Target: Kidneys, stimulates kidney tubule cells to reabsorb water, Hypothalamus portal osmoreceptor blood vessels Anterior Pituitary Gland, Stimulated:by GHRH release Inhibited: negative feedback by GH Target: Liver, muscle, bone, cartilage Stimulates somatic growth, mobilizes fats, Stimulated: cervical/uterine stretching, infant sucking at breast Inhibited: lack of appropriate neural stimuli Target: uterus, stimulates uterine contractions, initiates labour, milk ejection, Hyposecretion: diabetes insipidus Hypersecretion: SIADH Diabetes insipidus - polyuria, polydipsia Neurogenic DI - insufficient amounts of ADH Nephrogenic DI - inadequate renal response to ADH