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This Concept Map, created with IHMC CmapTools, has information related to: Gout, guanine is deaminated to Xanthine, Chris Turtle does not have, but is predisposed for Tophi, Chris Turtle pertinent medical history includes high blood pressure, Serum uric acid=8.8 leading to precipitation of urate crystals in the joints, hyperuricemia may suggest an increased risk for Gout, guanosine is converted to the purine base guanine, uric acid levels indicated as Serum uric acid=8.8, probenecid functions on renal tubules and therefore would not be a good treatment for a patient with mild kidney insufficiency, loop diuretic which can elevate uric acid levels, lactic acid which competes with excretion of uric acid levels, treatments for gout include allopurinol, Serum uric acid=8.8 leading to collections of urate crystals in the soft tissues, treatments for gout include febuxostat, Lasix 20 mg daily is a loop diuretic, Synovial fluid analysis from great toe revealed needle shaped crystals, negatively birefringent under polarizing microscopy, Hypoxanthine Are more soluble in the blood than uric acid, treatments for gout include probenecid, PRPP synthetase defect in gene resulting in increased activity, leads to increase production of purines, guanine via (with addition of PRPP) HGPRT, febuxostat in the liver inhibit Xanthine oxidase