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This Concept Map, created with IHMC CmapTools, has information related to: Hyperhomocysteinemia, Homocysteine in urine leading to the diagnosis of Homocysteinuria, Homocysteine receives a Methyl group, Highly reactive AA causes Redox reactions, can be used to produce Glutathione, MTHFR leading to elevated concentrations of Homocysteine, Redox reactions generating ROS, Compromised NT production via an unknown mechanism leading to neurological disease, Hyperhomocysteinemia treatment for which includes Vitamin B12, Serine catalyzed by Cystathionine beta-Synthase, Homocysteinuria treatment for which includes Vitamin B12, cysteine which can be used to, Glutathione which is an antioxidant, Hyperhomocysteinemia treatment for which includes Folic Acid, Folic Acid active form of which is Tetrahydrofolate, dUMP which can be converted to dTMP, Homocysteine in blood leading to the diagnosis of Hyperhomocysteinemia, Hyperhomocysteinemia resulting in Compromised NT production via an unknown mechanism, S-adenosylmethionine (SAM) is converted by methyltranferase to S-Adenosylhomocysteine (SAH), Gamma Cystathionase using pyridoxal phosphate, endothelial damage leading to Vascular Disease (including atherosclerosis)