WARNING:
JavaScript is turned OFF. None of the links on this concept map will
work until it is reactivated.
If you need help turning JavaScript On, click here.
This Concept Map, created with IHMC CmapTools, has information related to: Hyperhomocysteinemia_Updated, Hyperhomocysteinemia resulting in Compromised NT production via an unknown mechanism, MTHFR to 5-methyltetrahydrofolate (Dietary folate), methylcobalamin which transfers ITS Methyl group, endothelial damage leading to Vascular Disease (including atherosclerosis), MTHFR leading to elevated concentrations of Homocysteine, dUMP which can be converted to dTMP, Homocysteine combines with betaine, Patient has C677 --> T mutation variant in gene, Serine catalyzed by Cystathionine beta-Synthase, Methyl group forming methionine, Homocysteine receives a Methyl group, dTMP for DNA and RNA Synthesis, smooth muscle proliferation leading to Vascular Disease (including atherosclerosis), betaine homocysteine methyltransferase forming methionine, Cystathionine beta-Synthase which uses pyridoxal phosphate, cysteine which acts as a source of sulfur, Compromised NT production via an unknown mechanism leading to neurological disease, Homocysteinuria treatment for which includes Vitamin B6, Homocysteine in urine leading to the diagnosis of Homocysteinuria, Vitamin B12 the active form of which is reduced form of Cobalamin