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This Concept Map, created with IHMC CmapTools, has information related to: Ned Kendle_A7, Ned Kindle vital signs include respirations 18rpm, Ned Kindle is a 54 y/o Caucasian male, HCO3- reabsorption decrease in proximal tubules resulting in metabolic acidemia, damage to renal tubular epithelium in PCT and thick ascending limb causing decreased urinary excretion of titratable acids, persistent chest pain treated with percutaneous coronary intervention with stenting, damage to renal tubular epithelium in PCT and thick ascending limb causing HCO3- reabsorption decrease in proximal tubules, tubuloglomerular feedback leading to afferent arteriolar constriction, obstructed lumen of nephron causes increased Bowman's Space hydrostatic pressure, HCO3- reabsorption decrease in proximal tubules as seen in decreased HCO3 (20mEq/L), contrast from coronary angiogram, Decreased sodium reabsorption leading to macula densa sensing increased NaCl in Distal Convoluted Tubule, Ned Kindle has 2-day prior chief complaint of dyspnea, decreased GFR leading to elevated serum creatinine 3.0 (increased from 1.2 within 24 hours), nitroglycerin, metoprolol, and aspirin in order to reduce cardiac work, decreased renin release contraindicates administering Captopril, respiratory compensation in the form of increased respiratory rate, increased Bowman's Space hydrostatic pressure causes decreased GFR, Ned Kindle vital signs include Temp 99.2 F, elevated serum BUN 40 (increased from 18 within 24 hours) indicative of acute kidney injury (acute tubular necrosis) secondary to contrast induced nephropathy, damage to renal tubular epithelium in PCT and thick ascending limb decreasing ability to generate new bicarbonate