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RoughERBlue, Rough Endoplasmic Reticulum manufactures Proteins, membrane significance compartmentalization, Rough Endoplasmic Reticulum is membraneous with enzymes, ribosomes make Proteins, Proteins secreted by a cell, ribosomes makes it rough, Proteins significance synthesize, storage and export of important molecules, Proteins such as antibody, Rough Endoplasmic Reticulum manufactures membrane, endomembrane system which is in eukaryotic cells