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This Concept Map, created with IHMC CmapTools, has information related to: APC, professional APC includes B-cells, MHC I present antigen fragments by binding to CD4 receptors on T helper cell, non-professional APC including fibroblasts thymic epithelial cels thyroid epithelial cells glial cells vascular endothelial cells pancreatic beta cells, professional APC includes dendritic cells, MHC II present antigen fragments by binding to CD4 receptors on T helper cell, professional APC includes macrophages, Intracellular & Extracellular Antigens: presentation via MHC-I & II include MHC II, dendritic cells presents Intracellular & Extracellular Antigens: presentation via MHC-I & II, APC divided into non-professional APC, APC divided into professional APC, B-cells presents Extracellular Antigen binds to specific Ig receptors: presentation via MHC-II, MHC I present antigen fragments by binding to CD8 receptors on cytotoxic T-cells, macrophages presents Extracellular Antigens: presentation via MHC-II, MHC II present antigen fragments by binding to CD8 receptors on cytotoxic T-cells, Intracellular & Extracellular Antigens: presentation via MHC-I & II include MHC I