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This Concept Map, created with IHMC CmapTools, has information related to: reactive oxygen species, + proinflammatory cytokines: IL-1, IL-6, IL-10, IL-12, IL-15, TNFalpha, NO, IFNalpha and beta, PDGF, FBGF, VEGF, and others stimulate production of NO, superoxide, hydrogen peroxide, reactive O2 species (ROS), Mitochondria stimulate production of NO, superoxide, hydrogen peroxide, reactive O2 species (ROS), NO, superoxide, hydrogen peroxide, reactive O2 species (ROS) leading to acute inflammation, Peroxisomes stimulate production of NO, superoxide, hydrogen peroxide, reactive O2 species (ROS), NO, superoxide, hydrogen peroxide, reactive O2 species (ROS) leading to Single/double stranded breaks in DNA, immune responses may produce + proinflammatory cytokines: IL-1, IL-6, IL-10, IL-12, IL-15, TNFalpha, NO, IFNalpha and beta, PDGF, FBGF, VEGF, and others