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This Concept Map, created with IHMC CmapTools, has information related to: patho OPT, Warning Signs include nagging cough/hoarseness, Viruses such as HPV, autocrine stimulation of angiogenic factors, Viruses such as HBC/HCV, Active Immune Response which allows for pro-angiogenic factors, immune response involves B Lymphocytes, Warning Signs include change in wart or mole, Cancer can lead to Anticipated grieving, Decreased Immune System leads to chronic inflammation, immune response involves Cytotoxic T cells, Tumor suppressor genes inhibit cell division, Warning Signs include difficulty swallowing, Powerlessness because lack of control, autocrine stimulation of growth factors, Local Spread through lymphatic pathway, translocations causes excess production of proliferation factor, destroy cells with abnormal antigenic determinants, Lungs causing Arrest in Organs, cancer cells produce tumor markers, Local Spread need increased motility of individual tumor cells