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This Concept Map, created with IHMC CmapTools, has information related to: Patho Concept Map, lymph nodes near primary tumor, mutations like amplification, other organs like lung, epinephrine causing Diaphoresis, Impaired tissue integrity manifests as wounds, Bone by decreased RBC production, tumor-suppresor genes inactivated by loss of region of chromosome, Cells invade by Lytic Enzymes, fibrin network protects from Immune response, Immune response of Chronic Inflammation, Hyperuricemia may have fever, Metalloproteinase causes increased permeability, Bone by damaging bone marrow, Apoptosis controls excessive growth, Primary Tumor grows through angiogenesis & lymphatogenesis, Viruses like Epstein-Barr, collagenase leading to Bone pain/Pain, rapid increase of immature WBC leads to crowded cells, cytokines stimulate T cells, Immune response involves B cells