Quiz - Chapter 5
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1.
Which of the following is the BEST definition of incidence rate?
A.
Number of new cases of a disease reported during a specific period divided by the number of individuals in the population
B.
Proportion of the population affected by a disease at a specific point in time
C.
Effect of a specific risk factor
D.
Variation caused by the multiple effects of genes
2.
Which of the following statements is TRUE?
A.
Empiric risks are based on assumptions.
B.
Recurrence risk becomes higher if more than one family member is affected.
C.
An individual below the threshold of liability for a disease will have the disease.
D.
The recurrence risk for disease usually increases rapidly in more remotely related relatives.
3.
Which of the following describes a monozygotic twin?
A.
Twins who do not share traits
B.
Twins who share all traits
C.
Twins who form from double ovulation
D.
Concordant twins have a rate that varies across populations.
4.
Which of the following is NOT a congenital disease?
A.
Cleft lip
B.
Clubfoot
C.
Hydrocephaly
D.
Obesity
5.
Which of the following statements regarding coronary heart disease is TRUE?
A.
It is the leading killer of Americans.
B.
Atherosclerosis causes widening of the blood vessels.
C.
It is more common in females.
D.
Relative risk does not increase with relatives affected.
6.
A person presents with a diagnosis of hypertension. Which of the following statements regarding hypertension is TRUE?
A.
Systemic hypertension is seen in less than 5% of populations.
B.
Environmental factors do not cause hypertension.
C.
One of the most important factors affecting blood pressure is sodium intake.
D.
There is 100% correlation between family members and blood pressure.
7.
Which of the following is linked with breast cancer?
A.
BRCA1
B.
APC
C.
HLA II
D.
IDDM
8.
Which of the following is a TRUE statement regarding type 2 diabetes?
A.
Type 2 accounts for less than 10% of all cases of diabetes.
B.
There is no insulin production.
C.
These individuals experience insulin resistance.
D.
Type 2 diabetes is less common among obese persons.
9.
Which of the following is TRUE regarding Alzheimer disease?
A.
Alzheimer disease affects 40% of the population older than 65 years of age.
B.
Alzheimer disease is characterized by progressive dementia and memory loss.
C.
It has one gene locus.
D.
ADH is a key factor.
10.
Which of the following is not a general principle of genetic disorders?
A.
Complex genetic disorders that are strongly inherited tend to have a later age of onset.
B.
The presence of a genetic component to a disease does not mean that the course of the disease cannot be altered.
C.
Identification of a specific gene associated with disease can lead to more effective prevention and treatment of the disease.
D.
The more strongly inherited forms of genetic disorders are often due to single-gene inheritance.
Quiz - Chapter 5