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This Concept Map, created with IHMC CmapTools, has information related to: Biochem A1 G6P-DH Deficiency, NADP+ to NADPH, Pentose Phosphate Pathway provides the only mechanism of protection for red blood cells, NADPH reducing GSSG (oxidized glutathione), macrophages breaking down hemoglobin, dark urine indicative of elevated levels of urobilinogen, low hemoglobin count (7.5 g/dL) indicating hemolytic anemia, H202 to H20, hemoglobin containing heme, diagnostic testing showing elevated total serum bilirubin (19 mg/dL), red blood cells against high oxidative stress, Glutathione peroxidase its low level of activity increases free radicals, red blood cells against high oxidative stress, G6PD decreasing conversion of glucose-6-phosphate, diagnostic testing showing G6PD of 2.27 enzyme units, unconjugated bilirubin bound to albumin, H202 causing Hg denaturation, high oxidative stress upregulates levels of HMOX1/2, hepatocyte converted to conjugated bilirubin, Glutathione peroxidase its low level of activity increases H202, red blood cells against high oxidative stress