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This Concept Map, created with IHMC CmapTools, has information related to: CBL A1 Lethargy - Septic Shock, Benjamin Sellick presents w/ tachypnia, TNF-α enhances phaocytosis, anterior hypothalamus changing set point temperature, platelet adhesion to blood vessel wall, blood brain barrier stimulates prostaglandin production, blood vessel wall in capillaries, TNF-α crosses blood brain barrier, fluid leakage in tissues increasing edema, organ failure consistent with septic shock, macrophages release IL-1, anaerobic glycolysis increasing lactic acid production, macrophages releasing TNF-α, edema lowering blood volume, capillaries decreaess blood supply, TNF-α activates CRP production, blood stream travels to liver, CRP production enhances opsonization, hypoxemia shifts to anaerobic glycolysis, IL-6 activates CRP production, gas exchange decreasing O2 in tissues