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Deze Concept Map heeft informatie gerelateerd aan: RTK-pathway goede, MMP9 degradation extracellular matrix (ECM), point mutations or substitutions effect Gastrointestinal cancer, xenobiotic response element (XRE) expression MMP9, AhR-ARNT binds xenobiotic response element (XRE), Benzo[a]pyrene (BaP) binds Aryl hydrocarbon Receptor (AhR), CYP1A1 and CYP1B1 gene (P450-family) formation BaP diol epoxide, extracellular matrix (ECM) allowing metastasis and invasion of a tumor Gastrointestinal cancer, BaP diol epoxide formation DNA-adducts, c-myc increased cell proliferation Gastrointestinal cancer, Aryl hydrocarbon Receptor (AhR) dimer AhR-ARNT, DNA-adducts resulting in point mutations or substitutions, xenobiotic response element (XRE) expression CYP1A1 and CYP1B1 gene (P450-family), xenobiotic response element (XRE) expression c-myc, Aryl Hydrocarbon Receptor Nuclear Translocator (ARNT) formation AhR-ARNT, Aryl hydrocarbon Receptor (AhR) and Aryl Hydrocarbon Receptor Nuclear Translocator (ARNT)